An Overview of the Adaptive Behaviour Profile in Young Children with Angelman Syndrome: Insights from the Global Angelman Syndrome Registry

About this research

Using information contributed by families to the Global Angelman Syndrome Registry, this study explored communication, motor skills, daily living skills and behaviour in 204 children with Angelman syndrome under six years of age.

The research found that many communication, motor and adaptive skills were associated with age, showing that young children with Angelman syndrome continue to develop skills as they grow. It also identified differences by genetic type, particularly in communication, with children with a non-deletion aetiology showing advantages in some communication skills.

The study demonstrates the value of parent-reported Registry data in building a better understanding of development in Angelman syndrome and identifying areas that may benefit from targeted early intervention.

Read the full publication

The full paper is open access and available through Advances in Neurodevelopmental Disorders.