Factors associated with sleep disturbances in children and adolescents with Angelman Syndrome

Authors: Geraldine Leader, Chloe Killeen, Sally Whelan, Rory Coyne, Megan Tones & Arlene Mannion
Published: 2024
Journal: Sleep Medicine




About this research

Using data contributed by families to the Global Angelman Syndrome Registry, this study investigated sleep disturbances in 212 children and adolescents with Angelman syndrome and explored their relationship with other characteristics including behaviour, communication, gastrointestinal symptoms, epilepsy and early-life health history.

The study found important differences related to anxiety, with anxiety identified as a predictor of sleep disturbance. Sleep disturbances were also significantly associated with aspects of communication, including the ability to use spoken words and computerised communication devices.

The findings highlight the value of looking across different areas of Registry data to better understand factors associated with sleep difficulties in Angelman syndrome and help inform future research and clinical care.

Read the full publication

The full paper is open access and published in Sleep Medicine.

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